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Gender Score Development in the Berlin Aging Study II: A Retrospective Approach

Referierte Aufsätze Web of Science

Ahmad Tauseef Nauman, Hassan Behlouli, Nicholas Alexander, Friederike Kendel, Johanna Drewelies, Konstantinos Mantantzis, Nora Berger, Gert G. Wagner, Denis Gerstorf, Ilja Demuth, Louise Pilote, Vera Regitz-Zagrosek

In: Biology of Sex Differences 12 (2021), 15, 10 S.


In addition to biological sex, gender, defined as the sociocultural dimension of being a woman or a man, plays acentral role in health. However, there are so far few approaches to quantify gender in a retrospective manner inexisting study datasets. We therefore aimed to develop a methodology that can be retrospectively applied to assessgender in existing cohorts. We used baseline data from the Berlin Aging Study II (BASE-II), obtained in 2009–2014from 1869 participants aged 60 years and older. We identified 13 gender-related variables and used them toconstruct a gender score by using primary component and logistic regression analyses. Of these, nine variablescontributed to a gender score: chronic stress, marital status, risk-taking behaviour, personality attributes:agreeableness, neuroticism, extraversion, loneliness, conscientiousness, and level of education. Females and malesdiffered significantly in the distribution of the gender score, but a significant overlap was also found. Thus, we wereable to develop a gender score in a retrospective manner from already collected data that characterizedparticipants in addition to biological sex. This approach will allow researchers to introduce the notion of genderretrospectively into a large number of studies.

Keywords: Gender, Sex, Aging, Berlin Aging Study II, BASE-II, Gender score

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