We introduce multi-trait analysis of GWAS (MTAG), a method for joint analysis of summary statistics from genome-wide association studies (GWAS) of different traits, possibly from overlapping samples. We apply MTAG to summary statistics for depressive symptoms (Neff = 354,862), neuroticism (N = 168,105), and subjective well-being (N = 388,538). As compared to the 32, 9, and 13 genome-wide significant ...
In:
Nature Genetics
50 (2018), 2, 229-237
| Patrick Turley, Raymond K. Walters, Omeed Maghzian, Aysu Okbay, James J. Lee, et al.