Poor Glucose Regulation is Associated with Declines in Well-Being among Older Men, but not Women

Abstract

Glucose regulation is a key aspect of healthy aging and has been linked to brainfunctioning and cognition. Here, we examined the role of glucose regulation for withinpersonlongitudinal trajectories of well-being. We applied growth models to data fromthe Berlin Aging Study II (N = 1,437), using insulin resistance as an index of glucoregulatorycapacity. We found that poor glucose regulation (higher insulin resistance)was consistently associated with lower levels of well-being among older men, but notwomen. Our study provides novel evidence for the relevance of glucose regulation forwell-being among older men.